Clinical Significance
Rheumatoid Factor (RF) is an immunoglobulin M protein, produced by body’s immune system. This protein attacks the body’s tissues as it mistakenly identifies them as a foreign entity. Rheumatoid factor test determines the level of rheumatoid factor in your blood to diagnose rheumatoid arthritis. Higher RF concentrations are often linked to autoimmune disorders such as rheumatoid arthritis and Sjogrens syndrome. Other conditions that may elevate RF concentration in the blood include hepatitis, viral or bacterial infections, and endocarditis. There is also a gradual rise in RF levels with age.
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NEPHELOMETRY
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Rheumatologists, general medicine
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12
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SERUM
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N
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